| 세션명 | 콜로이드 및 분자조립 부문위원회 (I) |
|---|---|
| 발표장 | 제3회장 |
| 논문코드 | 1L3-5 |
| 발표일 | 2021-10-21 |
| 발표시간 | 16:00-16:25 |
| 논문제목 | Hydrolysis-Driven Viscoelastic Transition in ABA Triblock Copolyether Hydrogels with Acetal Pendants |
| 발표자 | 김병수 |
| 발표자 소속 | 연세대학교 |
| 저자 | 김병수† |
| 소속 | 연세대학교 |
| 논문초록 | While the hydrolytic cleavage of ester groups is widely exploited in degradable hydrogels, the scission at the midst of chain backbones can bring dramatic changes in the mechanical properties of the hydrogels. However, the predictive design of the mechanical profile of the hydrogels is a complex task, mainly due to the randomness of the location of chain scission. To overcome this challenge, we herein present degradable ABA triblock poly(ethylene oxide)-based hydrogels containing an A-block bearing acetal pendant, which provides systematically tunable mechano-temporal properties of the hydrogels. In particular, hydrophobic endocyclic tetrahydropyranyl or exocyclic 1-(cyclohexyloxy)ethyl acetal pendants are gradually cleaved by acidic hydrolysis, leading to the gel-to-sol transition at room temperature. Most importantly, a series of dynamic mechanical analyses coupled with ex situ NMR spectroscopy revealed that the hydrolysis rate can be orthogonally and precisely tuned by changing the chemical structure and hydrophobicity of acetal pendants. This study provides a new platform for the development of versatile degradable hydrogels in a highly controllable manner. |
THE POLYMER SOCIETY OF KOREA